By Steven M. Dinh, John DeNuzzio, Ann Comfort
content material: Cogelation of hydrolyzable cross-linkers and poly(ethylene oxide) dimethacrylate and their use as managed unencumber cars / Jennifer Elisseeff, Winnette McIntosh, Kristi Anseth, and Robert Langer --
Temperature-sensitive polymer method developed with sodium alginate and poly(N, N-dimethylaminoethyl methacrylate-co-acrylamide) / S.H. Yuk, S.H. Cho, H.B. Lee, and M.S. Jhon --
Pulsatile drug supply according to a complexation-decomplexation mechanism / A.M. Lowman and Nicholas A. Peppas --
Gel-coated catheters as drug supply structures / Stevin H. Gehrke, John P. Fisher, James F. McBride, Stephen M. O'Connor, and Huajie Zhu --
Novel ethylene glycol-containing, pH-sensitive hydrogels for drug supply purposes : "molecular gates" for insulin supply / Christie M. Hassan and Nicholas A. Peppas --
Overcoming the outside barrier with synthetic clever companies of gear / Gregor Cevc --
pH oscillation of a drug for temporal supply / Steven A. Giannos and Steven M. Dinh --
pH-hysteresis of glucose permeability in acid-doped LCST hydrogels : a foundation for pulsatile oscillatory drug unencumber / J.-C. Leroux and R.A. Siegel --
managed supply utilizing cyclodextrin know-how / Z. Helena Qi and Christopher T. Sikorski --
Inclusion compounds as a method to manufacture managed free up fabrics / L. Huang and A.E. Tonelli --
Liposomal supply platforms for phototherapeutic brokers / P.W. Taylor --
Intracellular supply of liposomal contents utilizing pH-and light-activated plasmenyl-type liposomes / Oleg V. Gerasimov, Nathan Wymer, Derek Miller, Yuanjin Rui, and David H. Thompson --
Conditionally solid liposomes for gene supply / S.C. Davis and F.C. Szoka, Jr. --
basic stories of DNA adsorption and hybridization on strong surfaces / Lynn Anne Sanguedolce, Vincent Chan, Steven E. McKenzie, Saul Surrey, Paolo Fortina, and David J. Graves --
software of neural networks to optimize flux profiles for transdermal platforms / R.T. Kurnik, J. Jona, and B. Jasti.
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Additional info for Intelligent Materials for Controlled Release
Since Κ tends to be independent of concentration for size exclusion while Κ is highly concentration dependent for ion exchange and ion exclusion, this result supports the hypothesis of ordinary size exclusion for nonionic solutes (7). ; ACS Symposium Series; American Chemical Society: Washington, DC, 1999. 52 Enhanced Loading Study. Table V demonstrates that the loading techniques developed for bulk gels are also applicable to gel-coated catheters. Low ovalbumin sorption by the PEO gel-coating is expected based upon size exclusion theory and this is observed by the modest loading with pure buffer solution.
ACS Symposium Series; American Chemical Society: Washington, DC, 1999. 7 ± 0 . 5 100 that seen when the gel and solute are oppositely charged. Also, water releases the unbound solute, not the change in pH as when the gel and solute are oppositely charged. PEO-gel coated catheters and various solutes are used in the investigation of nonionic solute effects (Table IV). First, the interaction of methyl orange (anionic, 327 Da) and PEO gel (nonionic) is examined. The nonionic character of the PEO gel eliminates the need for catheter pretreatment.
8. Vakkalanka,S. ; Brazel,C. ; Peppas,N. A. J. Biomater. ,Polym. Ed. 1996,8119. 9. ; Okano, T. Nature 1995, 374, 240. 10. Peppas,N. A. ,Science 1994, 263,1741. 11. Bell,C. ; Peppas,N. A. Adv. Polym. Sci. 1995, 122,125. 12. Bell,C. ; Peppas,N. A. Biomaterials 1996, 17,1203. 13. Bell,C. Controlled Release 1996, 39,201. 14. Bell,C. Biomater. ,Polym. Ed. 1996,7,671. 15. ; Scranton,A. ; Peppas,N. A. Macromolecules 1990, 23,4944. 16. Lowman,A. ; Peppas,N. A. Macromolecules 1997, 30,4959-4965. 17. Harland,R.