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Additional info for Current Aspects of the Neurosciences: Volume 4
1988). Let us now examine the experimental evidence for a role of gangliosides in neural plasticity. 42 L. F. Agnati, M. Zoli, G. Biagini, et al. In vitro Studies The main biological effects of gangliosides on biochemical mechanisms and trophic responses obtain in vitro are summarized in Table 1. l In vitro 3 Neuroglial, retinotectal and neuromuscular interaction and recognition GDlb, GM2, GTlb In vitro 4 Cell growth modulation Bovine brain gangliosides, GMl, GM3 In vitro 5 Increased neuron survival GMl In vitro, in vivo 6 Modulation of glial cell morphology Bovine brain gangliosides, GMl, GDla In vitro 7 Modulation of synapse morphology GM2,GM1 In vitro, in vivo 8 Modulation of synaptic transmission, NT release and metabolism: Polysialogangliosides, GMl Bovine brain gangliosides In vitro 9 Effect Ganglioside Neuritogenesis In vivo In vivo serotonin GMl,GQlb In vitro, in vivo 10 glutamate GMl,GTlb In vitro 11 acetylcholine Bovine brain ganglioside GMl.
Lin, Y. and Baldino, F. Jr (1985b). Detection of neuropeptide mRNA in rat brain by in situ hybridization with radio labelled synthetic oligonucleotide probes. Nucleosides Nucleotides, 4, 261 Baldino, F. -F. and Lewis, M. E. (1989). High resolution in situ hybridization histochemistry. Meth. , 168, 761-777 Baldino, F. Jr and Davis, L. G. (1986). Glucocorticoid regulation of vasopressin messenger RNA. In In situ Hybridization in Brain (ed. G. R. Uhl). Plenum Press, New York, pp. 97-116 Baldino, F.
Card, J. , Lewis, M. E. and Baldino, F. Jr (1988). Neuronal localization of prosomatostatin mRNA in rat brain with in situ hybridization histochemistry. J. Comp. , 273, 558--572 Forster, A. , Mcinnes, J. , Skingle, J. C. and Symons, R. H. (1985). Non-radioactive hybridization probes prepared by the chemical labeling of DNA and RNA with a novel reagent, photobiotin. Nucl. , 13, 745 Freed, W. , Perlow, M. , Hoffer, B. J. and Wyatt, R. J. (1980). Restoration of dopaminergic function by grafting of fetal rat substantia nigra to the caudate nucleus: long-term behavioral, biochemical and histochemical studies.