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By Z. Hugh Fan

Introduces the reader to Circulating Tumor Cells (CTCs), their isolation strategy and research, and commercially to be had structures -Presents the historic standpoint and the review of the sector of circulating tumor cells (CTCs) -Discusses the state-of-art equipment for CTC isolation, starting from the macro- to micro-scale, from confident focus to adverse depletion, and from biological-property-enabled to Read more...

summary: Introduces the reader to Circulating Tumor Cells (CTCs), their isolation process and research, and commercially on hand structures -Presents the historic viewpoint and the review of the sector of circulating tumor cells (CTCs) -Discusses the state-of-art tools for CTC isolation, starting from the macro- to micro-scale, from optimistic focus to unfavorable depletion, and from biological-property-enabled to physical-property-based methods -Details commercially to be had CTC structures -Describes post-isolation research and medical translation -Provides a word list of medical phrases concerning CTCs

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34. , and Akiyoshi, T. (1998) Detection of ras gene mutations in peripheral blood of carcinoma patients using CD45 immunomagnetic separation and nested mutant allele specifi amplification International Journal of Oncology, 12, 1333–1338. 35. J. et al. (1998) Detection and characterization of carcinoma cells in the blood. Proceedings of the National Academy of Sciences of the United States of America, 95, 4589–4594. 36. A. and Feeley, B. S. Kompala and P. Todd), American Chemical Society, Washington, DC, pp.

J. et al. (1998) Detection and characterization of carcinoma cells in the blood. Proceedings of the National Academy of Sciences of the United States of America, 95, 4589–4594. 36. A. and Feeley, B. S. Kompala and P. Todd), American Chemical Society, Washington, DC, pp. 268–288. 37. A. (1994) A model system for the enrichment of tumor cells from peripheral blood and bone marrow using immunomagnetic ferrofluids Progress in Clinical and Biological Research, 389, 593–600. 38. R. (1989) A rapid sample preparation technique for flow cytometric analysis of immunofluorescenc allowing absolute enumeration of cell subpopulations.

Et al. (1993) Differential expression of proliferationassociated molecules in individual micrometastatic carcinoma cells. Journal of the National Cancer Institute, 85, 1419–1424. 23. , Passlick, B. et al. (1996) Frequency and prognostic significanc of isolated tumour cells in bone marrow of patients with non-small-cell lung cancer without overt metastases. Lancet, 347, 649–653. 24. Folkman, J. (1971) Tumor angiogenesis: therapeutic implications. New England Journal of Medicine, 285, 1182–1186. 25.

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